Mix carbon nanotubes and asbestos together (metaphorically) and you get an explosive mix—at least if news coverage of the latest publication coming out of Professor Ken Donaldson’s team is anything to go by. The research—published on-line today in Nature Nanotechnology—is the first to explicitly test the hypothesis that long carbon nanotubes behave like long asbestos fibres in the body.
In brief, the study (which I was a co-author on) used an established method to test whether a fibrous material has the potential to lead to the disease mesothelioma—a cancer of the outer lining of the lungs that can take decades to develop following exposure. In the method, samples of material are injected into the abdominal space of mice, where inflammation and the formation of granulomas in the lining tissue (the mesothelium) are studied over a seven-day period. Previous research has established that the combined presence of fibres, inflammation and granulomas is a very strong indicator that mesothelioma will occur in the long-term. While the method uses lining of the abdominal space, it is highly predictive of what happens in the same tissue surrounding the lungs, if it is exposed to durable fibres. Read the rest of this entry »